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Center for Disease Control
Framework for Infertility Prevention and Control
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Click here to access links to the information below at the Center for Disease Control's web page on "Assisted Reproductive Technology".


  • 1998 Assisted Reproductive Technology Success Rates
    [National Summary and Fertility Clinic Reports]

    The 1998 report of pregnancy success rates is the fourth report to be issued under the Fertility Clinic Success Rate and Certification Act. The report includes a national report that uses information from 360 U.S. fertility clinics to provide an in-depth national picture of ART; fertility clinic tables that provide ART success rates for each clinic that submitted and verified its 1998 data; and appendices containing a glossary of terms and lists of reporting and nonreporting clinics in the United States.


  • Contribution of Assisted Reproductive Technology and Ovulation-Inducing Drugs to Triplet and Higher-Order Multiple Births— United States, 1980–1997.

    Pregnancies associated with assisted reproductive technology (ART) and drugs that induce ovulation are more likely to result in multiple births than spontaneously conceived pregnancies in the United States. Triplet and higher-order multiple births are at greater risk than singleton births to be preterm, low or very low birth weight, which may result in higher infant morbidity and mortality. This report estimates the connection between these birth outcomes and ART and ovulation-inducing drugs in 1996 and 1997. It also summarizes the trends that indicate ART and the use of ovulation-inducing drugs have increased the ratio of triplet and higher-order multiple births during the 1980s and most of the 1990s. [Source: MMWR, June 23, 2000/ 49(24);535-8.]


  • 1997 Assisted Reproductive Technology Success Rates 
    [National Summary and Fertility Clinic Reports]

    The 1997 report of pregnancy success rates is the third report to be issued under the Fertility Clinic Success Rate and Certification Act. The report includes a national report that uses information from more than 300 U.S. fertility clinics to provide an in-depth national picture of ART; fertility clinic tables that provide ART success rates for each clinic that submitted and verified its 1997 data; and an appendix containing a glossary of terms and lists of reporting and nonreporting clinics in the United States.


  • Live-Birth Rates and Multiple-Birth Risk Using In Vitro Fertilization

    To maximize birth rates, physicians who perform in vitro fertilization (IVF) often transfer multiple embryos, but this increases the multiple-birth risk. Live-birth and multiple-birth rates may vary by patient age and embryo quality. One marker for embryo quality is cryopreservation of extra embryos (if embryos are set aside for cryopreservation, higher quality embryos may have been available for transfer). The study found that, the risk of multiple births from IVF varies by maternal age and number of embryos transferred. Embryo quality was not related to multiple birth risk but was associated with increased live-birth rates when fewer embryos were transferred. [Source: JAMA. 1999;282:1832-1838.]


  • 1996 Assisted Reproductive Technology Success Rates
    [National Summary and Fertility Clinic Reports]

    The 1996 report of pregnancy success rates is the second to be issued. The report includes a national report that uses information from 300 U.S. fertility clinics to provide an indepth national picture of ART; fertility clinic tables that provide ART success rates for each clinic that submitted and verified its 1996 data; and an appendix containing a glossary of terms and lists of reporting and nonreporting clinics in the United States.


  • Implementation of the Fertility Clinic Success Rate and Certification Act of 1992: A Model Program for the Certification of Embryo Laboratories

    A Model Program for the Certification of Embryo Laboratories The Fertility Clinic Success Rate and Certification Act of 1992 (Pub. L. 102-493, 42 U.S.C. 263a-1 et seq.) required the Secretary, Department of Health and Human Services, through the CDC, to develop a model program for the certification of embryo laboratories, to be carried out voluntarily by interested states. This notice sets forth the model certification program requirements, including definitions, administrative requirements, and embryo laboratory standards. The model program incorporates comments received by CDC on the proposed model certification program that was published in the Federal Register on November 6, 1998 (63 FR 60178). From the Division of Laboratory Systems, Public Health Practice Program Office, CDC.


  • Assisted Reproductive Technology: Embryo Laboratory

    This site links to the (1) January 1999 report entitled Survey of Assisted Reproductive Technology: Embryo Laboratory Procedures and Practices (119 pages); and (2) Proposed Model Certification Program for Embryo Laboratories as required by the Fertility Clinic Success Rate and Certification Act of 1992. From the Division of Laboratory Systems, Public Health Practice Program Office, CDC.


  • 1995 Assisted Reproductive Technology Success Rates National Summary and Fertility Clinic Reports

    This report gives consumers and potential assisted reproductive technology (ART) users an idea of a woman's average chances of having a pregnancy and a live birth by using ART. The report includes a national summary that uses the information from all reporting fertility clinics to provide an indepth national picture of ART; fertility clinic reports that provide ART success rates for 259 clinics in the United States; and an appendix containing a glossary of terms used in the national and clinic reports.


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